BIOE 598

Spring 2020 Part of Term 1

Part of Term 1
Jan 21-May 6

Special Topics

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Credit: 1 TO 4 hours.

Subject offerings of new and developing areas of knowledge in bioengineering intended to augment the existing curriculum. See Class Schedule or departmental course information for topics and prerequisites.

May be repeated in the same or separate terms if topics vary to a maximum of 12 hours, but no more than 8 in any one term.

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BIOE 598 class schedule data for spring 2020
CRN	Type	Section	Time	Day	Location	Instructor	Section Details
45455	Lecture	AL	12:30PM -1:50PM	TR	2233 Everitt Laboratory	Sirk, S	Part of Term: 1 Date Range: 01/21/20-05/06/20 Credit: 4 hours Section Info: Students will explore concepts surrounding the field of immunoengineering, with a focus on understanding engineering approaches in both basic and translational research, as applied to the immune system and its manipulation for disease intervention and management. Students will rigorously investigate design principles underlying immunologically-based therapies and diagnostics. Critical analysis of scientific findings will be facilitated through instructor-led lectures, student-led literature discussions, and in-class activities and homework. Through activities and assignments, students should gain a deeper understanding of the underlying physical, chemical, and biological components that have facilitated immunogengineering advances, with an emphasis on developing novel, innovative solutions to address limitations in existing technology. Assignments, exams, and in-class activities will focus on critical analysis and thoughtful evaluation of data and conclusions, as well as effective written and oral communication skills. Restriction(s): Restricted to students in the Bioengineering, Chemical Engrg, Chemical & Biomolecular Engr, School of Molecular & Cell Bio, or Materials Science & Engineerng department.
60232	Lecture	GU	3:30PM -4:50PM	TR	2233 Everitt Laboratory	Underhill, G	Part of Term: 1 Date Range: 01/21/20-05/06/20 Credit: 4 hours Section Title: Stem Cell Bioengineering Section Info: Application of engineering approaches for the quantitative analysis of stem cell biology, including stem cell genetics and stem cell microenvironments. Design principles underlying stem cell-based therapies and diagnostics. Stem cell biomanufacturing. Restriction(s): Restricted to students in the Chemical & Biomolecular Engr, Chemical Engrg, School of Molecular & Cell Bio, Materials Science & Engineerng, or Bioengineering department.
68804	Lecture	LEC	2:00PM -3:20PM	TR	2233 Everitt Laboratory	Smith, A	Part of Term: 1 Date Range: 01/21/20-05/06/20 Credit: 4 hours Section Info: Technologies for Cancer Diagnosis and Therapy provides an introduction to how cancer is diagnosed and treated, focusing on related fundamental concepts in cancer biology and bioengineering. One major goal is for students to become comfortable integrating principles from physics, chemistry, engineering, and biology related to current strategies for understanding, detecting, and treating cancer. A second major goal is for students to understand and assess innovative solutions to current limitations in the field, and to use this information to generate a research proposal in the format of an NIH R21, which will be written and reviewed throughout the course term. The materials and content are designed for first year graduate students and senior undergraduate students from diverse majors. Recommended Prerequisites: BIOE 206 and CHEM 232, or equivalent knowledge. Restriction(s): Restricted to Graduate - Urbana-Champaign.
53713	Lecture	MAA	2:00PM -4:50PM	W	3117 Everitt Laboratory	Anastasio, M	Part of Term: 1 Date Range: 01/21/20-05/06/20 Special Approval: Advisor Approval Required Credit: 4 hours Section Title: Theoretical Image Science
64638	Lecture-Discussion	NIE	5:00PM -6:20PM	TR	2233 Everitt Laboratory	Nie, S	Part of Term: 1 Date Range: 01/21/20-05/06/20 Special Approval: Departmental Approval Required Credit: 4 hours Section Title: Cancer Nanotechnology Section Info: This is a graduate level course for students who are interested in learning nanotechnology and its applications in biology and medicine. Key topics include: (1) cancer biology and clinical oncology, (2) fundamentals of nanoscience, (3) principles of nanoscale engineering, (4) major classes of nanoparticles and nanostructures, and (5) nanomedicine - technologies and applications Restriction(s): Restricted to students in the Bioengineering department.
46896	Lecture	PJ	1:00PM -1:50PM	MWF	1306 Everitt Laboratory	Jensen, P Wyllie, R	Part of Term: 1 Date Range: 01/21/20-05/06/20 Credit: 4 hours Section Info: All engineers perform experiments. Whether they be “wet-lab” or simulated, experiments test the limits of our hypotheses and drive our understanding. Often engineers want to go beyond validating their theories and models. Engineers want the best designs – the optimal combination of cost, reliability, performance, and usability. This course presents a systematic framework for optimizing experiments and models. Using both experimental data and computer simulations, students will explore methods to efficiently search large design spaces. Restriction(s): Restricted to Graduate - Urbana-Champaign.
66022	Lecture	PS	9:30AM -10:50AM	MW	106B3 Engineering Hall	Gaj, T	Part of Term: 1 Date Range: 01/21/20-05/06/20 Credit: 4 hours Section Title: Quantitative Biotechnology Section Info: Offers first year graduate students in Bioengineering an opportunity to be exposed to the modern biotechnologies which sparked a Renaissance in current biology and biomedicine. For each weekly topic, we will do an in-depth review of various methods including the conventional/traditional protocols and the newly developed techniques. The scientific articles to be reviewed in class emphasize high precision, high spatial/temporal resolution, high-throughput, molecular accuracy, sensitivity and real-time imaging. Two students will be paired up to present each week's article and lead the discussion. The course consists of studies on the Central Dogma of Biology (DNA, RNA, and Protein) as well as cellular organelles and cell imaging. Restriction(s): Restricted to students in the Bioengineering department.
64989	Lecture	RXB	12:30PM -1:50PM	TR	1103 Siebel Center for Comp Sci	Bhargava, R Gaskins, R Pool, M	Part of Term: 1 Date Range: 01/21/20-05/06/20 Section Title: The Tissue Microenvironment Section Info: Advanced concepts of the complexity and heterogeneity of tissue microenvironments and their role in directing cell behavior and function in health and disease. Emphasis will be on comparing and contrasting the physio-chemical rate processes that govern the function of stem cell niches and solid tumor microenvironments. Topics will include: (i) Cell migration, mitosis, apoptosis, and differentiation; (ii) Cellular responsiveness to soluble and immobilized factors that mediate interactions between cells, with extracellular matrix, and growth factor communication; (iii) Biophysical and bioengineering aspects of mechanotransduction, the process through which living cells sense and respond to their mechanical environment. Students will conduct a semester-long team project for additional credit. Prerequisite: Prior coursework in and working knowledge of cellular and molecular biology.
68834	Lecture	TL	5:00PM -6:20PM	TR	3217 Everitt Laboratory	Lu, T	Part of Term: 1 Date Range: 01/21/20-05/06/20 Credit: 4 hours Section Info: Systems biology is the study of systems of biological components, which may be molecules, cells, organisms or entire species. Being highly complex, their behaviors are hard to predict from the properties of individual parts. Instead, it often requires holistic, quantitative measurements mathematical modeling of the groups of the interacting components. This course offers an introduction to the fundamental concepts, quantitative characterizations, and modeling methodologies underlying systems biology. Systems of study include modules and global structures ubiquitous in gene regulation, metabolism and signal transduction. Examples include functional modules such as feed-forward loops, switches and oscillators and systems composed of these modules. Mathematical models based on differential equations are used throughout the course to describe the dynamics of biological systems. A series of functional properties emerging from biological systems including modularity, ultrasensitivity, robustness, adaptation and optimality are examined and discussed. Altogether, the course outlines basic design principles ubiquitous in biological networks. Course Prerequisite: MATH 285 or equivalent Restriction(s): Restricted to students in the Chemical & Biomolecular Engr, Chemical Engrg, School of Molecular & Cell Bio, Materials Science & Engineerng, Physiology and Biophysics, Physics, Physics, or Bioengineering department.